Abstract: Adopting reference ADC,and driving the adaptive filter by the difference of the main ADC and reference ADC's quantized data,is a novel and popular background calibration approach for pipeline ADCs.In this method, LMS algorithm is applied to eliminate the harmonic distortion.In order to research this calibration method,a senior simulation model based on Simulink is presented in this paper.A 10-b,50-Ms/s,1.5-b/stage structure pipeline ADC with background calibration is modeled and simulated.Simulation results show that,with calibration,the resolution of the ADC can be improved and the power consumption can be reduced.