Abstract: Unidirectional Zero-feedback transmission of data and control signal is realized by physical isolation technology, and an error control method is proposed to decrease bit error rate (BER) and data packet loss problems,and to improve high-speed data transmission reliability. Man-machine interface is designed to control transmission process, adopting LVDS signal to decrease error bit rate. Making use of double SRAM in ARM to store data packet alternately, and designing read and write thread to decrease data packet loss rate. Theory and unidirectional data import system test prove that the method decrease BER and packet loss rate effectively, and accuracy rate of the import data reaches 99.999%, when the import rate is 5 Mb/s.